NLM DIR Seminar Schedule
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Dec. 17, 2024 Joey Thole
Training set associations drive AlphaFold initial predictions of fold-switching proteins -
Dec. 10, 2024 Amr Elsawy
AI for Age-Related Macular Degeneration on Optical Coherence Tomography -
Dec. 3, 2024 Sarvesh Soni
Toward Relieving Clinician Burden by Automatically Generating Progress Notes -
Nov. 19, 2024 Benjamin Lee
Reiterative Translation in Stop-Free Circular RNAs -
Nov. 12, 2024 Devlina Chakravarty
Fold-switching reveals blind spots in AlphaFold predictions
Scheduled Seminars on Dec. 14, 2021
Speaker
Benjamin Lee
Time
11 a.m.
Presentation Title
Where is everyone? The strange case of the missing viroids
Location
Zoom
Contact NLMDIRSeminarScheduling@mail.nih.gov with questions about this seminar.
Abstract:
New viruses are being discovered in droves thanks to high throughput sequencing. This is not true of viroids, pure RNA parasites so small that they encode no proteins. The comparative dearth of newly discovered viroids could be due to genuine rarity or it could be that, due to their extremely small size, viroids are lost in the vast quantities of data. By curating a database of all known sequences and developing a purpose-built pipeline for viroid and viroid-like RNA discovery, we show that there is indeed significant diversity of these agents present within metatranscriptomic samples.