NLM DIR Seminar Schedule

UPCOMING SEMINARS

RECENT SEMINARS

Scheduled Seminars on Feb. 11, 2025

Speaker
Po-Ting Lai
Time
11 a.m.
Presentation Title
Enhancing Biomedical Relation Extraction with Directionality
Location
Hybrid - TEAMS

Contact NLMDIRSeminarScheduling@mail.nih.gov with questions about this seminar.

Abstract:

Biological relation networks contain rich information for understanding the biological mechanisms behind the relationship of entities such as genes, proteins, diseases, and chemicals. The vast growth of biomedical literature poses significant challenges updating the network knowledge. The recent Biomedical Relation Extraction Dataset (BioRED) provides valuable manual annotations, facilitating the development of machine-learning and pre-trained language model ap-proaches for automatically identifying novel document-level (inter-sentence context) relationships. Nonetheless, its annotations lack directionality (subject/object) for the entity roles, essential for study-ing complex biological networks. Herein we annotate the entity roles of the relationships in the Bi-oRED corpus and subsequently propose a novel multi-task language model with soft-prompt learning to jointly identify the relationship, novel findings, and entity roles. Our results include an enriched Bi-oRED corpus with 10,864 directionality annotations. Moreover, our proposed method outperforms existing large language models such as the state-of-the-art GPT-4 and Llama-3 on two benchmarking tasks.

Microsoft Teams

Meeting ID: 224 443 106 522
Passcode: 5he64w7k
________________________________________