NLM DIR Seminar Schedule

Abstract:

The etiology of human chronic diseases is not fully understood. A large proportion of genetic heritability to diseases still remains elusive. Furthermore, the identification of other layers of –omic markers, such as DNA methylation, protein, and metabolite markers, remains challenging, even though a growing body of literature supports crucial roles of relevant markers in etiology of many diseases. In this talk, Dr. Wu will talk about several integrative multi-omics (genomics, transcriptomics, methylomics, proteomics, and metabolomics) studies to identify novel susceptibility genes and biomarkers for prostate and pancreatic cancer. He will also discuss the ongoing efforts for identifying population-specific and tissue-specific biomarkers for relevant diseases across racial and ethnic diverse populations.